Collaborative Research Centre / Transregio 296

Local Control of Thyroid Hormone Action (LOCOTACT)

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Published: 04 April 2022

Astrid Westendorf follows LOCOTACT Spokesperson Dagmar Führer as Vice-Rector for Research and Early-Career Researchers

Since April 2018 LOCOTACT spokesperson Dagmar Führer was the Vice-Rector for Research and Early-Career Researchers ath the University of Duisburg-Essen.

From April 2022 on, Prof. Dr. Astrid Westendorf follows Dagmar Führer in this importiant function. We wish Prof. Westendorf all the best for this new task.

Published: 29 March 2022

Four young scientists received LOCOTACT iRTG MD Fellowships 2022!

Like in 2021, the iRTG is happy to support four new MD candidates with fellowships! 
 
Tobias Bolte examines the role of thyroid hormone action in human cortical development (Project P04; PI: Prof. Peter Kühnen).
Jakob Gloge investigates thyroid hormone effects on ethanol-induced hepatocyte damage (Project P18; PI: Prof. Lars Möller).
Katharina Kotzur characterizes the potential of seletive deiodinase inhibitors in intact cells in vitro (Project P16; PI: Prof. Josef Köhrle).
Elena Schmaler studies the impact of a moderate thyroid hormone deficiency on cholestatic liver disease in male mice (Project P18; PI: PD Dr. Denise Zwanziger).
 
Welcome to LOCOTACT, good luck with your projects and congratulations to all of you!
Published: 22 March 2022

LOCOTACT at the 65th German Congress of Endocrinology (DGE) Annual Meeting

With its own symposium, LOCOTACT was present at this year’s annual meeting of the German Congress of Endocrinology (DGE). Originally planned to take place in Baden-Baden, Germany, the congress committee decided to go for another virtual event. 

On Saturday, 19.03.2022, the LOCOTACT symposium was chaired by Professor Dagmar Führer-Sakel (Essen) and Professor Jens Mittag (Lübeck). During the symposium, our CRC/TR 296 members Dr. Helge Müller-Fielitz, (Lübeck), Professor Lars Möller (Essen), and Professor Henrik Oster (Lübeck) gave insights in their scientific research. LOCOTACT members were present in various sessions of the congress; among them PIs Dr. Steffen Mayerl (P19), Professor Joachim Spranger (P15), and iRTG students Nuria López Alcántara (P14), and Julia Maier (P12).

Prior to opening of the DGE annual meeting, Professor Dagmar Führer-Sakel was invited to give a statement in the online press conference. In this context, she gave our consortium a stage and presented the topics and aims of LOCOTACT to the attending journalists. You can access a record of the press conference here: DGE Congress press conference
 
Following the press conference, Medical Tribune published a report about LOCOTACT:
Medical Tribune LOCOTACT
 
See you at the DGE congress in 2023!
Published: 21 March 2022

ERC Consolidator Grants for outstanding Scientific Work

We congratulate Professor Peter Kühnen (Charité – University Hospital Berlin) and PD Timo Müller (Helmholtz-German Research Centre for Environmental Health) for receiving a Consolidator Grant each from the European Research Council. This highly prestigious grant honours groundbreaking research in Europe and thus awards our CRC/TR members Peter Kühnen and Timo Müller for their excellent work at scientific frontiers.
 
Find the current press releases from both universities here:
 
Helmholtz-Munich
 
Charité Berlin
Published: 18 February 2022

Funding period extended - UMEA Clinician Scientist Program enters next round

The program "Excellence in Medicine: Clinician Scientist Academy of the University Medical Center Essen" (UMEA) will be funded by the German Research Foundation (DFG) with approximately 2.6 million euros for another three years.

Since 2018 UMEA is headed by LOCOTACT spokesperson Dagmar Führer, who is also Vice-Rector for Research and Early-Career Researchers at the University of Duisburg-Essen. 

We congratulate for this great achievement.

Published: 18 February 2022

Research Data Management in Medical and Biomedical Sciences

Did you ever search for your own data and lose track of your documentation? Did you ever fail to reproduce someone elses research? Wouldn’t it be nice if your data would be well organized right from the beginning of a project? Good research data management can make the difference! In this workshop, we give insights how to manage and document data throughout data collection, analysis, publication, long-term storage, archiving, and how to prepare your data for reuse.
On 20 and 22 June 2022 (9:00 am - 12:30 pm) the INF project and the Research Data Services (RDS) of the University of Duisburg-Essen (https://www.uni-due.de/rds/) will jointly offer in cooperation with the ZB MED (https://www.zbmed.de/) a workshop on Research Data Management (RDM) in Medical and Biomedical Sciences in the CRC/TR 296 LOCOTACT. The workshop will provide a general introduction to the basics of RDM in addition to best practices, subject-specific requirements, and examples from the National Research Data Infrastructure (NFDI).
The two-day workshop will take place online and is intended for all-qualification-level (bio-)medical researchers, especially for PhD/MD students of the CRC/TR 296 LOCOTACT, postdocs and PIs are also welcome to join. The course will be taught in English. 
 
Registration: until 30.05.2022 via This email address is being protected from spambots. You need JavaScript enabled to view it. with subject: RDM workshop
Published: 10 February 2022

LOCOTACT Lectures - Miguel López

We thank Prof. Miguel López for his fantastic talk entitled “Obesity Wars: A new hope, hypothalamic AMPK targeting”.
 
Prof. López gave insights in his work and his stunning findings about hypothalamic AMPK targeting in the context of obesity treatment. His research group “NeurObesity” is based in the Center for Research in Molecular Medicine and Chronic Diseases (CIMUS) at the University of Santiago de Compostela (USC), Spain.
 
We are curious about his future investigations and wish him a successful research year 2022.

Published: 05 February 2022

Heike Heuer invited to Dutch Endocrine Meeting 2022

We are delighted about the invitation of Heike Heuer to the Dutch Endocrine Meeting 2022 in Noordwijkerhout, the Netherlands, on 03. and 04.02.2022.

On the second day of the Meeting, Heike Heuer held her talk on "Thyroid hormone transporters as cell-specific gate-keepters".

Published: 04 February 2022

Karl-Oberdisse-Preis 2022

Congratulations to Dr. Steffen Mayerl (LOCOTACT PI) who has been awarded with the Karl-Oberdisse-Preis 2022!
The "Karl Oberdisse Prize" of the North Rhine-Westphalian Society of Endocrinology and Diabetology is awarded for the best clinical or experimental work in the field of endocrinology and diabetology, which has been developed to a substantial extent in North Rhine-Westphalia by a physician or scientist.

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Central Office

Administration

University of Duisburg-Essen
c/o University Hospital Essen
Department of Endocrinology, Diabetes and Metabolism
Phone: +49 201/723 - 5350
E-Mail: locotact@uk-essen.de

CRC/TR296

As a truly interdisciplinary research consortium LocoTact is well equipped to meet the challenge of defining local control of TH action and to develop translational strategies tailored to cells and tissues with the perspective to capitalise on the power of the hormone to treat rare or prevalent diseases.

Speaker at UDE

Prof. Dr. Dr. Dagmar Führer-Sakel
Dagmar.Fuehrer-Sakel@uk-essen.de

Co-Speaker at UzL

Prof. Dr. Jens Mittag
jens.mittag@uni-luebeck.de

Co-Speaker at Charité

Prof. Dr. Peter Kühnen
peter.kuehnen@charite.de

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