Projects
TH transporters at brain barriers
Impact of TH on tanycyte functions and the relevance on central regulation of the liver and hormone uptake
Transporter expression and TH action in the brain
TH action in hiPSC-derived brain organoids
Novel pharmacotherapies for the treatment of central TH deprivation associated with Mct8/Oatp1c1 deficiency
THRA deficiency and Allan-Herndon-Dudley-Syndrome: Defects of local TH function during human brain development
A brain imaging approach to TH function in consequence to mutations in TH receptors and transporter proteins
Local TH transport and action in ischaemic brain injury
TH transporters in myelin formation and regeneration
Local TH action in acute and chronic ischaemic heart disease
Role of the enigmatic TRα2 isoform in regulating cardiac TH function
TH receptor α1 at the crossroad of autonomic and cardiac functions in mice
TH receptor-clock interaction in NAFLD development
Control of cellular TH metabolism in human and mouse NASH
Liver-specific TH activity in NAFLD and NASH
Strategies to increase local T3 availability in liver
Control of deiodinase type 1 (DIO1) expression and its protective function in human hepatocytes
Hepatic TH signalling in acute and acute-on-chronic liver injury
Impact of TH transport on seizure generation
Establishment and provision of human pluripotent stem cell (hiPSC)-derived 2D and 3D cellular models of brain, liver and heart and technologies for their analysis
Integrated Research Training Group (iRTG)
Research Data Management (INF)
