Collaborative Research Centre / Transregio 296

Local Control of Thyroid Hormone Action (LOCOTACT)

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Published: 30 September 2024

46th Annual Meeting of the European Thyroid Association

In 2024, the annual meeting of the European Thyroid Association (ETA) took place on September 7-10 in Athens, Greece.

We are proud that many LOCOTACT researchers have been invited and selected for presentations.

Dagmar Führer-Sakel (Spokesperson): A Year in Cancer
Lars Möller (P10+P18): Symposium (basic)
Sebastian Hönes (P18): Research Grant Winner Presentation
Rajas Sane (P16): Young Investigator (basic)
Andrea Alcaide Martín (P19): Young Investigator (basic) 
Nina Härting (P11): Topic Highlights
Riccardo Dore (P12): Symposium (translational) 
Manuela Kowalczyk (P18): Oral Session 
Androniki Alevyzaki (P01): Oral session 
Yingfu Chen (P15): Oral Session
Elena Schmaler (P18): Oral Session
Joshua-Joel Richter (P09): Oral Session

Our warmest congratulations go to Rajas Sane who has been honored with the Young Investigator Award - well done!

Furthermore, our spokesperson Dagmar Führer-Sakel presented the application of Essen as the venue for 48th Annual ETA Meeting in 2027, which was approved by the general assembly. Thus we look forward to welcoming the community to Essen.

Collage Eta 2024I comp

 

Published: 29 July 2024

ETA Project Research Grant for LOCOTACT PostDoc Akila Chandrasekar

Congratulations to our PostDoc from P02, Akila Chandrasekar, who has been awarded this year's ETA Project Research Grant (Basic). Akila will receive €20,000 to study the "Role of tanycytic TSH receptor in a Graves’ disease model".

We are proud of you and wish you a very successful project!

Published: 12 July 2024

ETA Project Research Grant for LOCOTACT PostDoc Christina Wenzek

We are proud that our PostDoc Christina Wenzek was awarded this year's ETA Project Research Grant (Basic/Translational). With this grant Christina receives 20.000 € for her research on the "Impact of TH receptor α signaling on T cell function during disease". 

On behalf of all LOCOTACT members, we wish her every success with her project!
Dagmar Führer, Jan Tuckermann, Heike Heuer and Nicole Unger after the LOCOTACT Lecture in Essen. Photo: Steffen Mayerl
Published: 26 June 2024

LOCOTACT Lectures – Jan Tuckermann

We were honoured to have the President of the German Society of Endocrinology (DGE), Jan Tuckermann, as our second guest lecturer in June. During his visit to the Department of Endocrinology in Essen, he gave a lecture on "How Glucocorticoids Regulate Immune Metabolism to Control Inflammation and Insulin Resistance". The professor, from the Institute of Comparative Molecular Endocrinology at the University of Ulm, gave details of glucocorticoid receptor signalling, its influence on immunemetabolism and the effect of anti-inflammatory metabolites.

We would like to thank Prof. Tuckermann once again for coming to Essen and giving an exciting talk on his impressive results, which provoked an interesting and fruitful discussion.

Published: 25 June 2024

iRTG Summer Retreat 2024

The iRTG Summer Retreat 2024 took place on 24.06.2024 in Essen. About 20 PhD and MD candidates met in person to give a presentation about their doctoral project and to receive the “Certificate of Completion” of the doctoral programme of the CRC/TR 296 LOCOTACT.

In the evening we had the nice opportunity to enjoy the sunny weather with a barbecue and cold drinks in the Gruga Park in Essen, to get together and also to do some sportive activities.

It has been a great pleasure to welcome our PhD and MD candidates once again in Essen. We wish you all the best luck for wrapping up your projects and writing your thesis! You have done extremely well and we are proud that we could guide you on your journey!!!

Published: 21 June 2024

LOCOTACT Lectures – Olaf Hiort

The June 2024 LOCOTACT Lecture was held by the renowned paediatric endocrinologist Olaf Hiort from the Universität zu Lübeck and the University Hospital Schleswig-Holstein. The speaker of the CRC sexdiversity raised the question "Do we have to (re-)define sex in biomedical research", explained the effect of hormones on the regulation of sex development and pointed out the complexity of defining biological sex. 

We are delighted that Prof. Hiort accepted our invitation and would like to thank him for raising important questions in an inspiring lecture and for the fruitful discussion.

Published: 23 May 2024

LOCOTACT at ETA Masterclasses on Advanced Thyroid Cancer

The first ETA Masterclasses on Advanced Thyroid Cancer took place in Barcelona from 15-17 May 2024. LOCOTACT Speaker Dagmar Führer was one of the eleven international experts who met with 40 young attendees, among them two clinician scientists from Essen, to discuss diagnosis and treatment of advanced thyroid cancer. 

Published: 21 May 2024

LOCOTACT Lectures – Ludovic Vallier

We were honoured to have Ludovic Vallier from the BIH Centre for Regenerative Therapies and the Max Planck Institute for Molecular Genetics in Berlin as our guest speaker at the May 2024 LOCOTACT Lecture. The liver researcher gave a presentation on "Everything you always wanted to know about in vitro systems to model liver diseases in vitro" and talked about his research on advanced in vitro liver models derived from hiPSCS and the advantages of 3D-cell culture and co-culture techniques.

We would like to thank the speaker for his insightful lecture and the lively discussion.

Published: 17 May 2024

Poster Award for LOCOTACT Project at ECE 2024 in Stockholm

LOCOTACT PI Heike Heuer presented newest data of project P01 in an oral and a poster presentation at this year's annual meeting of the European Congress of Endocrinology (ECE) taking place in Stockholm, 11-14 May 2024. Her presentation "Thyroid Hormone Transporter Mct8/Oatp1c1 deficient mice display impaired CNS capillary network formation" was awarded with the Poster Award 2024 - Basic.

Congratulations to Heike Heuer and her whole team working on this exciting project!

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Central Office

Administration

University of Duisburg-Essen
c/o University Hospital Essen
Department of Endocrinology, Diabetes and Metabolism
Phone: +49 201/723 - 5350
E-Mail: locotact@uk-essen.de

CRC/TR296

As a truly interdisciplinary research consortium LocoTact is well equipped to meet the challenge of defining local control of TH action and to develop translational strategies tailored to cells and tissues with the perspective to capitalise on the power of the hormone to treat rare or prevalent diseases.

Speaker at UDE

Prof. Dr. Dr. Dagmar Führer-Sakel
Dagmar.Fuehrer-Sakel@uk-essen.de

Co-Speaker at UzL

Prof. Dr. Jens Mittag
jens.mittag@uni-luebeck.de

Co-Speaker at Charité

Prof. Dr. Peter Kühnen
peter.kuehnen@charite.de

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